Pycnogenol Binds to Collagen & Elastin

The fibrous proteins collagen and elastin are critical “building block” components of many different body tissues, lending strength, stability and flexibility to blood vessels, skin, cartilage, tendons, ligaments and more.

Unfortunately, as we grow older some enzymes – including matrix metalloproteinases (MMPs) – are known to break down collagen and elastin. This degradation is associated with visible signs of aging in the skin, such as wrinkles and sagging, along with internal structural problems with joint health, arterial stiffness and more.

Maintaining flexible and abundant collagen and elastin is a desirable health goal for anyone seeking skin health, joint health and anti-aging benefits – and Pycnogenol might just help.

Pycnogenol has a natural affinity for collagen and elastin. As PYC binds to these proteins, it lends structural support along with targeted delivery of its antioxidant and inflammation-modulating properties.

This collagen-and-elastin-binding activity has been suggested to account for Pycnogenol benefits in the body’s many connective tissues, helping PYC to:

  • Reinforce and protect arterial walls, which are made of collagen and elastin
  • “Seal” leaky capillaries, potentially assisting with broken capillaries
  • Promote supple, flexible and healthy blood vessels for cardiovascular health
  • Protect cartilage’s “cushiness,” keeping it plump and resilient for joint comfort
  • Maintain, nourish and protect all connective tissues throughout the body
  • Promote anti-aging benefits by smoothing wrinkles for youthful-looking skin

In addition to helping strengthen collagen and elastin throughout the
body, research suggests that PYC may block some enzymes that
are responsible for the degradation of collagen and elastin.

Pycnogenol-Collagen

Research shows Pycnogenol appears to block the activity of enzymes that eat away at collagen, suggesting a protective effect that may be useful for anti-aging programs.


Grimm, T., Schäfer, A., and Högger, P. “Antioxidant Activity and Inhibition of Matrix Metalloproteinases By Metabolites of Maritime Pine Bark Extract (Pycnogenol).” Free Radical Biology and Medicine 36 (2004): 811-822
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