Pycnogenol side effects are rarely reported; it seems to be well-assimilated and well-tolerated by the body. No serious adverse events have been noted in any of the many pine bark extract clinical trials with human subjects.
F.A.Q.: Is Pycnogenol Safe? Overall, an overwhelming majority of scientific evidence suggests that Pycnogenol is a safe, natural substance with beneficial properties for health.
PYC’s safety and tolerability may be rooted in the pristine coastal environment Pinus Maritima calls home, as well as the clean, eco-friendly water extraction that is used to draw out the bark’s active constituents.
Mild and transient adverse events that have been linked to PYC in research include:
- Gastrointestinal: Upset stomach, queasiness and bad breath have been reported.
- Skin: Dryness, itching, flaking, rash and hives have been reported.
- Blood sugar: A drop in blood sugar levels has been reported in some research.
- Urinary Issues: Increased urinary urges and frequency have been reported.
- Nervous System: Headaches, dizziness, vertigo and drowsiness have been reported.
Cautions: As with any nutritional supplement, Pycnogenol should always be taken under the direction of a qualified health professional. It should not be taken by women who are in their first trimester of pregnancy. PYC lowers blood sugar and reduces blood pressure, and should be used carefully by those with concerns in these areas, or who are taking medications for these conditions. PYC has anti-clotting properties that may exacerbate bleeding. Those with autoimmune problems, liver issues, and certain cardiovascular concerns are advised to take extra care with the supplement. Children may take the supplement, albeit with caution and under close supervision.